Company Overview

Ansella Therapeutics is specialty pharmaceutical company that leverages biomimetic sciences to develop novel therapeutics that improve healthcare outcomes. The company’s initial focus is on women’s health, specifically in the development of novel vaginal formulations.

Biomimetics is an interdisciplinary field in which principles from engineering, chemistry and biology are applied to the synthesis of materials, or synthetic systems that have functions that mimic biological processes. Biomaterials are any natural or synthetic material that interacts with any part of a biological system. Biomimetic designs can be used in regenerative medicine, tissue engineering and drug delivery.

Ansella Therapeutics utilizes its expertise in materials science and biomedical engineering to create unique, enhanced therapeutic approaches inspired by inherent anatomy, physiology, biochemistry, and endocrinology.

The company has launched its first product, Cerynë Intimate Care, for women with everyday vaginal dryness and designed for vulvovaginal application. Cerynë Intimate Care is the world’s first biomimetic formulation which works with your body to restore comfort and balance.

Cerynë Intimate care has been launched both directly to consumers and through physician channels as an intimate care product for vaginal dryness.

Ansella Therapeutics is developing a range of treatment that focus on Women’s Health including Menopause, Vaginal mucositis, Endometriosis, Uterine Fibroids and vaginal Infection.

Company overview

Avive Solutions is a MedTech company that has developed a next-generation automated external defibrillator (AED) and software solutions that revolutionizes the current sudden cardiac arrest (SCA) response. 

The device aims to significantly increase survival rates from SCA. 

The $3.5 billion global external defibrillators market is projected to have 9.7% compounded annual growth rate (CAGR) from 2024 to 2030. The AED market growth is  driven by legislation, property development and hospital groups, which has caused a shift in customer awareness and push for inbound sales models that the large players generally ignore in favor of entrenched distributor relationships.

The current SCA response system has a 10% survival rate, but when AEDs are used, the survival rate increases to over 40%.  The low AED usage is due to limited availability, improper maintenance, and a lack of connectivity in current AED machines. 

Avive’s automated external defibrillator (AED) device is a next-generation IoT (internet-of-things) device with complementary software solutions that has the ability to transform the existing flawed system for responding to Sudden Cardiac Arrest (SCA). Their system automates AED maintenance, tracks the AED, provides remote software updates, and automatically shares rescue data with emergency services, effectively eliminating the issues plaguing current aed machines. Their goal is to get an AED to a patient in under 4 minutes compared to the normal standard response time for emergency services which is 12 minutes. 

Cofounder: Sameer Jafri

Smeer is one of the Founders of Avive, and serves as the CEO. His most recent role prior to founding Avive was as the Founder & President of Saving Hearts Foundation, a non-profit based in Los Angeles that is focused on Sudden Cardiac Death (SCD) prevention. The foundation has hundreds of volunteers across the Greater Los Angeles Area, and physician support from industry leading cardiologists and electrophysiologists from UCLA, Kaiser Permanente, HCA, and others. Sameer received his Bachelor’s degree in Political Science from UCLA.

Cofounder: Rory Beyer

Rory is one of the Founders of Avive and serves as the President / COO. His most recent role prior to founding Avive was as a product design engineer at Apple, where he contributed to the development and design of future generation accessory products. Rory received his Bachelor’s degree in Electrical Engineering and Computer Science, as well as Mechanical Engineering from MIT. During his time at MIT, Rory held numerous leadership roles in MIT research projects, including among others the electronics development of a car powered completely by Aluminum fuel.

Cofounder: Moseley Andrews

Moseley is one of the Founders of Avive, and serves as the CTO. His past experience and passion has revolved around developing innovative healthcare technology. His most recent role prior to founding Avive was working as a researcher at the MIT Media Lab where he helped develop novel sensing and imaging techniques. Moseley received his Bachelor’s degree in Mechanical Engineering from MIT, and while obtaining his degree he led multiple engineering projects that included rehabilitation products for spinal cord, stroke, and brain trauma as well as keyhole neurosurgical instrument design.

Company overview

AWAK Technologies is a clinical-stage, medical device company that has developed a disruptive peritoneal dialysis (PD) device based on revolutionary new filtration technology developed in-house.

The Device aims to be first in the world for wearable dialysis device. .

Refine business model and expand markets  in the $120 billion Chronic Kidney Disease market   

The current treatment modalities are disruptive to the patient’s daily routine but also impose a heavy cost burden on patients, payers, and caregivers. Presently patients are required to be plugged to a machine in a dialysis center during the day or overnight at home, requiring either travel time and a flexible work schedule or limiting their mobility. 

Additionally these treatments require large amounts of water (several hundred of liters) and are power intensive, so there is also an incentive to develop new technologies which will require less energy and water. The high cost burden of in center treatment has led to a continuous shift in preference towards at home dialysis options. 

Awak technology runs on breakthrough sorbent-based regeneration technology that eliminates the current dependence on large volumes of dialysate and costly water treatment, while also being 20x smaller than in-center dialysis machines. These lightweight and portability features enhance a patient’s mobility which instils self confidence and psychological well being.

CEO: Suresha Venkataraya

Suresha is the Chief Executive Officer of AWAK Technologies. Prior to becoming CEO at AWAK Technologies, he worked for Hill-Rom, a US$5.4B medical devices company, as the Director for Front Line Care business, where he was responsible for developing and commercialising new products, and spearheading innovation culture. He has acquired deep domain expertise in areas such as Respiratory Care, ECG/Cardio, Remote Patient Monitoring and Therapy Surface Technologies. Suresha received a Masters in Computer Control Systems from Nanyang Technological University, Singapore, and A Bachelors  in Electronics and Communication Engineering from Visvesvaraya Technological University, India.

CMO: Mandar Gori

As the Chief Marketing Officer and Chief Business Officer at AWAK Technologies Pte Ltd, Mandar Gori leads Marketing, Clinical and Business Development departments. Prior to AWAK, Mandar was Deputy Director at A*STAR, Singapore’s premier R&D and commercialisation agency, where he successfully established programs to train and develop local MedTech talent and give them an in-depth understanding of other regional healthcare markets. Mandar has a MBA from Nanyang Business School, Singapore, MS in Healthcare Informatics from University of Alabama at Birmingham, US, and BE in Information Technology from Mumbai University, India. He also has several patents related to technologies in kidney care under his name.

Company overview

Edeavors ENV-101 is a second-generation Hedgehog inhibitor with a highly favorable efficacy and side-effect profile compared to the molecules currently in the market. ENV-101 inhibits target pathway by ~90% at all tested doses.

Currently Hedgehog inhibitors are indicated for basal cell carcinoma. Significant data indicates the pathway involvement in fibrosis of the lungs. ENV-101 represents a significant improvement on existing therapies for IPF and is expected to be the Best-in-Class Hedgehog Inhibitor.

Attractive white space in the market
IPF market estimated to be $8.8B by 2027. SOC (standard of care), i.e., Boehringer Ingelheim’s Nintedanib (Ofev) has current sales >$3B with <20% market penetration based on prescription data. Current SOC has poor tolerability and efficacy.

Roche acquired InterMune in 2014 for $8.3 billion for Pirfenidone (Esbriet), indicated for IPF. Esbriet lost exclusivity in 2022 and Ofev is expected to lose exclusivity in 2025; which gives the next blockbuster significant white space for pricing and reimbursement. Both Ofev and Esbriet have severe and limiting GI issues for patients which ENV-101 seems to address.

Cofounder: Dr. John Hood

Dr. Hood is a veteran of the California life science community who has founded and led several successful biotechnology companies in his 20-year career. He is currently Founder, CEO and Executive Chairman of Endeavor Biomedicines. Prior to that, John was the Founder and CEO of Impact Biomedicines (now owned by Bristol-Myers Squibb), the developer of fedratinib, which has subsequently been approved worldwide for the treatment of myelofibrosis. He began his career as Director of Research at TargeGen in 2001, where he co-discovered fedratinib. John is an inventor on 100+ patents and the author of 50+ scientific articles. He received his Ph.D. in Medical Physiology and a B.S. in Biochemistry from Texas A&M University.

Cofounder: Dr. Miguel de los rios

Miguel de los Rios is an entrepreneur focused on developing novel therapeutics to satisfy unmet needs in human medicine. Prior to Endeavor, he was Founder and CEO at Rift Biotherapeutics, a therapeutic antibody company focused on cancers. Prior to that Miguel served as Vice President of Research and Development at Sevion Therapeutics (formerly Fabrus, Inc.), a clinical stage therapeutics company focused in oncology and autoimmune disorders. Miguel founded Chimeros, Inc., a venture-backed biologics therapeutic company in 2003 while working to complete his PhD. He is lead author or inventor on 50+ publications, patents and patent applications. He received his Ph.D. in Biophysical Chemistry and a B.S. in Cell Biology, both at UC Santa Barbara.

Company overview

Enquyst Technologies is developing the next-generation biopharmaceutical manufacturing platform which aims to redesign the downstream bioprocess equipment to bring unprecedented advantages in cost, time, footprint, and speed to market at commercial scale.

The technology aims to be the industry standard for downstream processing.

Disrupt the business model and expand markets in the $400 billion biologics market

The current downstream processing for expensive biologics, gene therapy, and viral vectors is expensive, cumbersome, and is fraught with regulatory challenges across the manufacturing spectrum.

Additionally, these expensive therapeutics are generally out of reach for most emerging countries. Enquyst plans to democratize the manufacturing process by bringing next-generation manufacturing that is fully continuous, reduces capital expenditure and operating expenditure by over 70%, reduces the footprint of manufacturing by over 70% and can reduce the time to setup a new facility from the current 5-years to under 3-years.

The technology can be game-changer for gene-therapy manufacturers, biosimilar companies, as well as early-stage biotech companies where product purification, separation, and product consistency can be the difference between success and failure.

CSO: Dr. DEE atwal

Dee has over 3 decades of experience in antibody engineering and development, covering multiple antibody programs now on the market. Dee has managed and led programs spanning oncology, autoimmune, inflammatory and CNS from discovery through clinical development.

founder: Dr. Jason Criscione

Dr. Criscione is an applied science and engineering entrepreneur with a unique expertise that covers a variety of different scientific disciplines. Dr. Criscione has 9+ years of experience in successfully building and leading interdisciplinary technical teams for start-up biotech and pharmaceutical companies. Dr. Criscione has published in numerous peer-reviewed, scientific journals, including, Nature Nanotechnology, Nature Materials, Biomaterials, JACS, ACS Nano, and Bioconjugate Chemistry. Dr. Criscione received his Ph.D. in Biomedical Engineering, his Mphil in Biomedical Engineering and a MS in Biomedical engineering from Yale University. He also received a MS in Physical Chemistry from Michigan State University and a BA with High Honors in Chemistry and a concentration in Neuroscience from Oberlin College.

Company Overview

Entalpi is a nascent Norwegian company developing an e-coaching smartphone app designed to optimize sports training and subsequent performance, as well as associated SaaS and e-commerce businesses. The company’s product seeks to digitize & scale the training methods and coaching insight developed by Olav Aleksander Bu, internationally-renowned triathlon coach.

The impact of his method has been demonstrated in his training of Norwegian triathletes Kristian Blummenfelt and Gustav Iden to world record-setting and international-championship performance levels. Entalpi is founded, owned, managed, and advised by Olav and a team of active triathlon competitors, sports nutrition/biology scientists, and sports entrepreneurs.

The AI aims to significantly improve health and performance

Performance and health data is today presented in tools with predetermined graphs and classifications based on old paradigms not utilizing the value of the raw data. This prevents professionals from advancing their understanding of what affects performance and makes it very difficult to create individualized performance interventions.

Entalpi’s engine allows devices to provide real-time biofeedback to guide the user on what improves health and performance and increases the joy of exercise and a sense of achievement.

Cofounder and CEO: Olav Aleksander Bu

Internationally renowned endurance coach who in recent years has made history within endurance sports and triathlon through training several athletes to World Championship and Olympic gold medals.

Cofounder: Roger Holthe Olsen

Experienced CEO and serial tech entrepreneur with a strong track record in building and scaling digital companies and e-commerce.

Cofounder: Aart Goossens

With a unique combination of degrees in exercise physiology and IT, Aart is a software developer fueled by a strong interest in both data and sports science.

Company Overview

Nettwork Holdings is a distribution and marketing services company, that enables effective and targeted distribution of multiple products across the life science and healthcare value chain.

We believe that an effective distribution strategy is paramount in the current healthcare environment, and for all young companies across devices, diagnostics, digital health, nutrition and wellness, having a defined distribution strategy is critical to success.

Through a powerful distributor network, we provide access to new markets for cutting-edge medical and diagnostics products in US, Europe, Africa, and Asia.

Our partners include large hospital networks, major suppliers and distributors of healthcare products and services, government organizations, and non-profit organizations.

Our distribution services include marketing, branding, sales and support with both clinical trial strategy and design and regulatory strategy.

Nettwork Holding’s unique marketing approach enables precise measurement of factors that lead to marketing success, higher profitability, and sustained margins. The Company emphasizes Econometric Models as opposed to traditional Attribution Models that often provide inaccurate results.

Company overview

An athlete-owned entity that supports non-drafting professional triathletes, the PTO is unique as a professional sports organisation in representing both pro women and men and through our athletes being self-determined co-owners

The organisation aims to be the infrastructure enabling the main streaming and monetization of triathlon.

The current triathlon Events primarily target mass amateur participants and operate on low production budgets, making them less appealing to broadcasters even with the high participation rates of around 35M athletes that triathlon achieves. However, PTO has forged partnerships with NBC, achieving viewership that surpasses established sports like PGA and MLS. 

The value lies in the ability to deliver a highly engaged audience to sponsors and advertisers. Triathlon has the sport’s most valuable audience – highest HHI of any sporting audience – with 44% of triathletes who consider it into financial decisions made at their place of business. 

Additionally, the triathlon audience is known to be elusive and difficult to reach, prompting advertisers to pay a premium to reach. Similar to the broader sports industry, revenues in triathlon come from sponsorship, broadcast rights, and fees from host cities for major events.

This organization can be a game changer for the triathlon industry through them building an infrastructure that enables the broadcast, sponsorship, and hosting of professional triathlon events all across the globe.

Executive Chairman: Chris Kermode

Mr. Kermode is a retired English professional tennis player, a former tournament director, and the former CEO & president of the Association of Tennis Professionals (ATP). Under his leadership, he transformed the ATP’s season-ending World Tour Finals at the London O2 Arena into the largest and most successful indoor tennis event in the world and launched the Next Gen Finals to showcase the world’s top tennis professionals aged under 21. During Kermode’s tenure at the ATP, the amount of prize money paid in men’s professional tennis increased more than 70%.Mr. Kermode has been on PTO’s board as Vice Chairman since July 2020, and as of October 2022 he became Executive Chairman.

CEO: Sam Renouf

Mr. Renouf has a proven track record of 13 years working on the business side of triathlons and has led former companies growth internationally. Before beginning to work at PTO he was the CEO at Motiv Group, which is a company that is entertainment focused for athletes, while there Mr. Renouf led many acquisitions across a range of different sports, including triathlons. He was also the former GM at ACTIVE Network further solidifying his experience in expanding a company into different areas globally. Mr. Renouf obtained his BSc from Loughborough University in Politics with Management, and a MBA from London Business school. He has been the CEO for PTO for four years and is well suited to continue to lead PTO’s growth.

Cofounder: Christophe Balestra

Mr. Balestra has 14 years of experience as a world renowned gaming executive in his position as Co-President at Naughty Dog (famous video game company). This experience as a leader within the technology industry puts him in a strong position to further strengthen PTO’s technological aspects and continue the growth of the company.

Company overview

Sanoculis has developed MIMS (Minimally Invasive Micro Sclerostomy), for treating glaucoma – the only minimally invasive procedure that delivers excellent reductions in intra-ocular pressure but leaves no implant in the eye. A MIMS procedure can be performed in about 5 minutes and requires significantly less operator skill, this means lower skilled operators can treat a higher volume of patients. The company is currently partnering with industry leader, Bausch & Lomb.

85% Medication reduction at 12 mo.

Statistically equivalent or superior reduction of IOP & medication versus all methods

Leaves no artificial materials or implants behind

Reduced side effects, complications, & tissue disruption and less complicated revisions

Fast learning curve/adoption ease for ophthalmic surgeons

Glaucoma drainage devices held the largest market share since 2021 and have been growing at the fastest CAGR in the category. A growing geriatric population and a high prevalence of Glaucoma is fueling growth in the surgical devices market.

Cofounder: Nir Israeli

Mr. Israeli brings 10 years of experience as a founder and CEO of 3 Israel-based tech startups, including glaucoma diagnostics company EyeOP. He holds a Masters of Business Administration in Marketing and Finance from the Recanati Business School of Tel Aviv University and a Bachelor’s of Science in Computer Engineering from the Technion. At Sanoculis, he leads a business team that has previously worked together. He is also a technical asset as a co-inventor of the Sanoculis intellectual property.

Cofounder: Vadim Shmukler

Mr. Shmukler provides 9 years of experience as a mechanical and systems engineer for the Israeli Defense Forces (as Group Leader) and the prominent materials science company Applied Materials. He has a decade-long collaborative history with the CEO on both the business and technical sides, also serving as a co-inventor of the Sanoculis IP alongside numerous other patents. He holds a Masters of Science and Bachelor’s in Mechanical Engineering from Tel Aviv University and the Technion, respectively.

Company overview

Sonrai Analytics is developing cutting-edge technology to enable discovery within precision healthcare. Sonrai’s ability to manage and analyze integrated data uniquely positions the company  to support biotech and pharma in the search for new drug development.

The Platform aims to elevate client data to expedite the R&d process for life science organisations. 

Bioinformatics and  data management is a large fast-growing market.

Enhancing efficiency in biopharma presents a substantial opportunity due to the exponential growth of scientific experiment datasets. Many biologists lack computational tools for rapid analysis, while research tracking in paper and spreadsheets hinders collaboration and reproduction. 

Biopharmaceutical industry professionals have revealed challenges with Omics data, emphasizing issues with quality, storage, FAIR compliance, integration, and analysis. An estimated 70-80% of biopharmaceutical environments lack FAIR compliance. studies suggests potential savings of $9-12 million for emerging BioPharma through a 40% reduction in data wrangling, leading to increased efficiency and improved scientific outcomes.

Sonrai’s capacity to consolidate diverse datasets within a unified platform, coupled with the strength of its robust and scalable infrastructure allows for their platform to effectively manage various data modalities, enabling applications in a variety of computational inputs allowing for novel correlations. The platforms able to combine and derive insights from multiple types of data, employing AI/ML and deep learning techniques to clean and integrate large multi-omics datasets in seconds.

Cofounder: Dr. Darragh McArt

Darragh is the co-founder and CEO of Sonrai Analytics since 2019.  Darragh’s more than 15 years of experience in translational bioinformatics and data analytics has allowed him to create a company that provides insights and solutions for businesses. Darragh has a background in research and has worked as a Research Fellow at CCRCB in Belfast, UK. Darragh McArt’s educational career includes a PhD in Bioinformatics from Ulster University, an MSc in Bioinformatics from Ulster University, and a BSc in Biology and Statistics from Maynooth University.

Cofounder: Dr. Deva Senevirathne

Deva Senevirathne is the co-founder of Sonrai Analytics and has ample experience in the bioinformatics and computational genomics space. By qualification, she is a computer scientist and a full-stack software engineer. She completed her primary education in Sri Lanka, and then obtained a BSc in Computer Science from University College Dublin.  She went on to pursue a Master’s in Bioinformatics and Computational Genomics from Queen’s University Belfast (QUB) followed by a PhD opportunity in Cancer research. As part of her efforts within the PhD program, she developed the first prototype of the InDRA framework which subsequently led to the creation of Sonrai Analytics.